Article
Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells.
Blood - 1 Jun 2007
Bowie Michelle B, Kent David G, Copley Michael R, Eaves Connie J
Abstract excerpt
Fetal hematopoietic stem cells (HSCs) regenerate daughter HSCs in irradiated recipients more rapidly than do adult HSCs. However, both types of HSCs divide in vitro with the same cell-cycle transit times, suggesting different intrinsically determined self-renewal activities. To investigate the me...
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