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Article

Autonomous behavior of hematopoietic stem cells.

Experimental hematology - 1 Dec 2000

Kamminga L M, Akkerman I, Weersing E, Ausema A, Dontje B, Van Zant G, de Haan G

Abstract excerpt

Mechanisms that affect the function of primitive hematopoietic stem cells with long-term proliferative potential remain largely unknown. Here we assessed whether properties of stem cells are cell-extrinsically or cell-autonomously regulated. We developed a model in which two genetically and phenotypically distinct stem cell populations coexist in a single animal. Chimeric mice were produced by transplanting...

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PMID: 11146167
DOI: 10.1016/s0301-472x(00)00543-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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