Article
FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells.
Blood - 2 Dec 2010
Liu Fei, Lee Jae Y, Wei Huijun, Tanabe Osamu, Engel James D, Morrison Sean J, Guan Jun-Lin
Abstract excerpt
Little is known about whether autophagic mechanisms are active in hematopoietic stem cells (HSCs) or how they are regulated. FIP200 (200-kDa FAK-family interacting protein) plays important roles in mammalian autophagy and other cellular functions, but its role in hematopoietic cells has not been...
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