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Article

Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium.

20 Feb 1996

Abstract excerpt

A major goal of experimental and clinical hematology is the identification of mechanisms and conditions that support the expansion of transplantable hematopoietic stem cells. In normal marrow, such cells appear to be identical to (or represent a subset of) a population referred to as long-term-culture-initiating cells (LTC-ICs) so-named because of their ability to produce colony-forming cell (CFC) progeny for >...

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PMID: 8643656
DOI: 10.1073/pnas.93.4.1470

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Source receipt: pubmed, retrieved 7 Sept 2026.

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