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Article

The replication rate of human hematopoietic stem cells in vivo.

Blood - 28 Apr 2011

Catlin Sandra N, Busque Lambert, Gale Rosemary E, Guttorp Peter, Abkowitz Janis L

Abstract excerpt

Hematopoietic stem cells (HSCs) replicate (self-renew) to create 2 daughter cells with capabilities equivalent to their parent, as well as differentiate, and thus can both maintain and restore blood cell production. Cell labeling with division-sensitive markers and competitive transplantation studies have been used to estimate the replication rate of murine HSCs in vivo. However, these methods are not feasible in...

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Identifiers

PMID: 21343613
DOI: 10.1182/blood-2010-08-303537
PMCID: PMC3099568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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