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Article

Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins.

Traffic (Copenhagen, Denmark) - 1 Mar 2007

Skånland Sigrid S, Wälchli Sébastien, Utskarpen Audrun, Wandinger-Ness Angela, Sandvig Kirsten

Abstract excerpt

The plant toxin ricin is transported from the plasma membrane via early endosomes and the Golgi apparatus to the endoplasmic reticulum. From this compartment, it enters the cytosol and inhibits protein synthesis. Lipid phosphorylation is an important regulator of vesicular transport, and in the present study we have investigated the role of the phosphatidylinositol (PI) 3-kinase hVps34 in retrograde transport of...

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Identifiers

PMID: 17319803
DOI: 10.1111/j.1600-0854.2006.00527.x

Genes

SNX4
SNX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins.PMID 17319803Read ↗

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