Article
Elevating PI3P drives select downstream membrane trafficking pathways.
Molecular biology of the cell - 15 Jan 2021
Steinfeld Noah, Lahiri Vikramjit, Morrison Anna, Metur Shree Padma, Klionsky Daniel J, Weisman Lois S
Abstract excerpt
Phosphoinositide signaling lipids are essential for several cellular processes. The requirement for a phosphoinositide is conventionally studied by depleting the corresponding lipid kinase. However, there are very few reports on the impact of elevating phosphoinositides. That phosphoinositides are dynamically elevated in response to stimuli suggests that, in addition to being required, phosphoinositides drive...
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