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Hepatitis B virus counters intracellular antiviral responses by saturating APOBEC/AID enzymes with rcDNA

2024-04-18

Abstract excerpt

Hepatitis B virus (HBV) causes severe liver disease by establishing persistent infection in human hepatocytes. Current medications suppress viral replication but cannot eliminate the virus from infected cells. Efforts are focused on modulating intracellular immunity to develop new therapies targeting the major genomic form of HBV, known as covalently closed circular DNA (cccDNA). One potential approach involves ut...

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Literature Corpus work
fefcfe34-dc61-5b4d-8ad2-01b82af481a0
DOI
10.22541/au.171340704.44470345/v1
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Hepatitis B virus counters intracellular antiviral responses by saturating APOBEC/AID enzymes with rcDNADOI 10.22541/au.171340704.44470345/v1
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