Article
Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.
The Journal of cell biology - 26 Feb 2007
Hou Yuqing, Qin Hongmin, Follit John A, Pazour Gregory J, Rosenbaum Joel L, Witman George B
Abstract excerpt
Intraflagellar transport (IFT), which is the bidirectional movement of particles within flagella, is required for flagellar assembly. IFT particles are composed of approximately 16 proteins, which are organized into complexes A and B. We have cloned Chlamydomonas reinhardtii and mouse IFT46, and show that IFT46 is a highly conserved complex B protein in both organisms. A C. reinhardtii insertional mutant null for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
