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Article

Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46.

The Journal of biological chemistry - 9 Jul 2010

Lucker Ben F, Miller Mark S, Dziedzic Slawomir A, Blackmarr Philip T, Cole Douglas G

Abstract excerpt

Intraflagellar transport (IFT) particles of Chlamydomonas reinhardtii contain two distinct protein complexes, A and B, composed of at least 6 and 15 protein subunits, respectively. As isolated from C. reinhardtii flagella, IFT complex B can be further reduced to a approximately 500-kDa core that contains IFT88, 2x IFT81, 2x IFT74/72, IFT52, IFT46, IFT27, IFT25, and IFT22. In this study, yeast-based two-hybrid...

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Source

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Identifiers

PMID: 20435895
DOI: 10.1074/jbc.M110.106997
PMCID: PMC2898376

Genes

IFT46
IFT52
IFT81
IFT88
IFT27
IFT74
IFT25
IFT22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46.PMID 20435895Read ↗

Analysis of interactions between intraflagellar transport proteins.Semantic proximity Read ↗

IFT57 stabilizes the assembled intraflagellar transport complex and mediates transport of motility-related flagellar cargo.Semantic proximity Read ↗

Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis.Semantic proximity Read ↗

Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.Semantic proximity Read ↗

Assembly of IFT trains at the ciliary base depends on IFT74.Semantic proximity Read ↗

Retrograde intraflagellar transport mutants identify complex A proteins with multiple genetic interactions in Chlamydomonas reinhardtii.Semantic proximity Read ↗

Intraflagellar transport (IFT) protein IFT25 is a phosphoprotein component of IFT complex B and physically interacts with IFT27 in Chlamydomonas.Semantic proximity Read ↗

The <i>Chlamydomonas reinhardtii</i> BBSome is an IFT cargo required for export of specific signaling proteins from flagellaSemantic proximity Read ↗

Tetrahymena IFT122A is not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body.Semantic proximity Read ↗

Review: Intraflagellar transport proteins in the retina.Semantic proximity Read ↗

IFT25 is required for the construction of the trypanosome flagellumSemantic proximity Read ↗

Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin.Semantic proximity Read ↗

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