Article
Genetic and phenotypic analysis of flagellar assembly mutants in Chlamydomonas reinhardtii.
Methods in cell biology - 1 Jan 2009
Iomini Carlo, Till Jacob E, Dutcher Susan K
Abstract excerpt
Conditional mutants for flagellar assembly (fla) provide a useful tool to study intraflagellar transport (IFT) at the molecular level, and provide a unique set of tools to analyze cilia. The analysis of IFT phenotypes of fla mutants at the permissive temperature by a quantitative image analysis approach identified four distinct phases of the IFT cycle and directly demonstrated structural and functional remodeling...
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