Article
TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children.
The Journal of clinical endocrinology and metabolism - 1 May 2007
Körner Antje, Berndt Janin, Stumvoll Michael, Kiess Wieland, Kovacs Peter
Abstract excerpt
CONTEXT: Variants in the transcription factor 7-like2 (TCF7L2) gene have been associated with an increased risk for type 2 diabetes in adults. To evaluate whether the five reported risk variants confer a higher risk for obesity and early impairment of glucose metabolism in children, we genotyped these risk variants of the TCF7L2 gene in a representative cohort of 1029 Caucasian children and an independent cohort...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.