Article
rs12255372 variant of TCF7L2 gene is protective for obesity in Mexican children.
Archives of medical research - 1 Aug 2011
Klünder-Klünder Miguel, Mejía-Benitez María Aurora, Flores-Huerta Samuel, Burguete-García Ana I, García-Mena Jaime, Cruz Miguel
Abstract excerpt
BACKGROUND AND AIMS: Variants in the transcription factor 7-like 2 (TCF7L2) gene are consistently associated with type 2 diabetes in adults, but the association of TCF7L2 with weight-related traits and body fat in humans is unclear. The aim of this study was to determine the relationship between the TCF7L2 gene (rs12255372) and obese phenotype in Mexican school-age children. METHODS: The study was performed in...
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