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TCF7L2 rs7903146 polymorphism association with diabetes and obesity in an elderly cohort from Brazil

5 May 2021

Abstract excerpt

Background Type 2 diabetes mellitus (T2DM) and obesity are complex pandemic diseases in the 21st century. Worldwide, the T allele rs7903146 in the TCF7L2 gene is recognized as a strong GWAS signal associated with T2DM. However, the association between the C allele and obesity is still poorly explored and needs to be replicated in other populations. Thus, the primary objectives of this study were to evaluate the...

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PMID: 33996288
DOI: 10.7717/peerj.11349

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