Article
Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth.
Diabetologia - 1 Mar 2011
Dabelea D, Dolan L M, D'Agostino R, Hernandez A M, McAteer J B, Hamman R F, Mayer-Davis E J, Marcovina S, Lawrence J M, Pihoker C, Florez J C
Abstract excerpt
AIM/HYPOTHESIS: Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been associated with type 2 diabetes in adults. However, it is not known whether TCF7L2 variation increases the risk of early onset type 2 diabetes. Using a case-control design, we examined whether the reported variants [rs12255372 (T/G) and rs7903146 (T/C)] are associated with type 2 diabetes in SEARCH for Diabetes in Youth...
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