Article
Evidence for a locus in 1p31 region specifically linked to the co-morbidity of asthma and allergic rhinitis in the EGEA study.
Human heredity - 1 Jan 2007
Dizier Marie-Hélène, Bouzigon Emmanuelle, Guilloud-Bataille Michel, Genin Emmanuelle, Oryszczyn Marie-Pierre, Annesi-Maesano Isabella, Demenais Florence
Abstract excerpt
OBJECTIVE: A recent genome scan conducted in French EGEA families led to detect linkage of 1p31 to either asthma or allergic rhinitis (AR) and more significantly to asthma associated with AR. The goal of the present study was to assess formally whether 1p31 is a linkage region shared by two different diseases, asthma and AR, or whether it is specific to the co-morbidity asthma plus AR. METHODS: We used two...
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