Article
Genome screen in the French EGEA study: detection of linked regions shared or not shared by allergic rhinitis and asthma.
Genes and immunity - 1 Mar 2005
Dizier M-H, Bouzigon E, Guilloud-Bataille M, Bétard C, Bousquet J, Charpin D, Gormand F, Hochez J, Just J, Lemainque A, Le Moual N, Matran R, Neukirch F, Oryszczyn M-P, Paty E, Pin I, Vervloet D, Kauffmann F, Lathrop M, Demenais F, Annesi-Maesano I
Abstract excerpt
In the sample of 295 French EGEA families with at least one asthmatic subject, a genome screen was conducted to identify potential linkage regions specific either to allergic rhinitis (AR) or to asthma as well as those shared by the two diseases. Two binary rhinitis phenotypes based on (1) diagnosis (ARbin1) and (2) symptoms (ARbin2) and a categorical ordered trait (ARcat) were considered. Asthma phenotype was...
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