Article
Asthma susceptibility variants are more strongly associated with clinically similar subgroups.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Nov 2016
Lavoie-Charland Emilie, Bérubé Jean-Christophe, Boulet Louis-Philippe, Bossé Yohan
Abstract excerpt
OBJECTIVE: Genome-wide association studies (GWAS) identified single nucleotide polymorphisms (SNPs) reproducibly associated with asthma. This study evaluated whether GWAS-nominated SNPs are more strongly associated with asthma patients sharing the same clinical characteristics in order to refine the role of recently identified genes. METHODS: Analyses were performed in unrelated French Canadian subjects (566...
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