Article
Indication of linkage and genetic heterogeneity of asthma according to age at onset on chromosome 7q in 107 French EGEA families.
European journal of human genetics : EJHG - 1 Nov 2001
Dizier M H, Besse-Schmittler C, Guilloud-Bataille M, Selinger-Leneman H, Kauffmann F, Clerget-Darpoux F, Demenais F
Abstract excerpt
It is generally believed that an early age at the onset of disease is associated with a stronger genetic component. Our aim here was to investigate both linkage and genetic heterogeneity of asthma, the latter corresponding to different genotype relative risks of a putative linked gene according to age at onset of asthma. This analysis was conducted in 107 French EGEA families with at least two asthmatic siblings,...
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