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Article

CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation.

Experimental hematology - 1 Mar 2007

Zhang Jinghang, Varas Florencio, Stadtfeld Matthias, Heck Susanne, Faust Nicole, Graf Thomas

Abstract excerpt

OBJECTIVE: Development of a mouse line permitting live imaging of cells expressing CD41/GpIIb as a means to study megakaryopoiesis. MATERIALS AND METHODS: The gene encoding yellow fluorescent protein (eyfp) was inserted by homologous recombination into embryonic stem cells at the start site of the gpIIb locus. A knockin mouse line, designated CD41-yellow fluorescent protein (YFP), was developed and was...

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Identifiers

PMID: 17309829
DOI: 10.1016/j.exphem.2006.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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