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Article

Induced Pluripotent Stem Cell-Derived Megakaryocytes and Platelets for Disease Modeling and Future Clinical Applications.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017

Borst Sara, Sim Xiuli, Poncz Mortimer, French Deborah L, Gadue Paul

Abstract excerpt

Platelets, derived from megakaryocytes, are anucleate cytoplasmic discs that circulate in the blood stream and play major roles in hemostasis, inflammation, and vascular biology. Platelet transfusions are used in a variety of medical settings to prevent life-threatening thrombocytopenia because of cancer therapy, other causes of acquired or inherited thrombocytopenia, and trauma. Currently, platelets used for...

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Identifiers

PMID: 28982668
DOI: 10.1161/ATVBAHA.117.309197
PMCID: PMC5675007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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