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Article

RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

PloS one - 1 Jan 2013

Suzuki Aae, Shin Jae-Won, Wang Yuhuan, Min Sang H, Poncz Morty, Choi John K, Discher Dennis E, Carpenter Chris L, Lian Lurong, Zhao Liang, Wang Yangfeng, Abrams Charles S

Abstract excerpt

RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and platelet release, in addition to having a role in platelet activation. These processes were previously studied using pharmacological inhibito...

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PMID: 23935982
DOI: 10.1371/journal.pone.0069315
PMCID: PMC3720647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23935982-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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