Article
ABCB1 and GST polymorphisms associated with TP53 status in breast cancer.
Pharmacogenetics and genomics - 1 Feb 2007
Nordgard Silje H, Ritchie Marylyn D, Jensrud Sigrid D, Motsinger Alison A, Alnaes Grethe I G, Lemmon Gordon, Berg Marianne, Geisler Stephanie, Moore Jason H, Lønning Per Eystein, Børresen-Dale Anne-Lise, Kristensen Vessela N
Abstract excerpt
BACKGROUND AND OBJECTIVE: Many environmental and genetic factors influence the development of chemoresistance. The goal of this study was to characterize the genetic variation in the ABCB1, GSTM1, GSTT1 and GSTP1 genes, as well as the haplotype structure in the ABCB1 gene. METHODS: Variants in th...
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