Article
Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes.
PloS one - 1 Jan 2015
Vymetalkova Veronika, Soucek Pavel, Kunicka Tereza, Jiraskova Katerina, Brynychova Veronika, Pardini Barbara, Novosadova Vendula, Polivkova Zdena, Kubackova Katerina, Kozevnikovova Renata, Ambrus Miloslav, Vodickova Ludmila, Naccarati Alessio, Vodicka Pavel
Abstract excerpt
Variations in the TP53 gene have been suggested to play a role in many cancers, including breast. We previously observed an association between TP53 haplotypes based on four polymorphisms (rs17878362, rs1042522, rs12947788, and rs17884306) and the risk of colorectal and pancreatic cancer. Based on these results, in the present study, we have investigated the same polymorphisms and their haplotypes in 705 breast...
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