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Article

Accelerated senescence of human peritoneal mesothelial cells exposed to high glucose: the role of TGF-beta1.

Laboratory investigation; a journal of technical methods and pathology - 1 Apr 2007

Ksiazek Krzysztof, Korybalska Katarzyna, Jörres Achim, Witowski Janusz

Abstract excerpt

Cellular senescence can be activated in response to noxious environmental stimuli. A senescent-like phenotype has been detected in the peritoneal mesothelium of mice exposed to high intraperitoneal glucose. We have sought to examine whether high glucose (HG) can induce the senescence program in human peritoneal mesothelial cells (HPMC) in vitro. Senescence of omentum-derived HPMC was induced by serial passages....

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Identifiers

PMID: 17297436
DOI: 10.1038/labinvest.3700519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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