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Article

Effect of High Glucose on Stress-Induced Senescence of Nucleus Pulposus Cells of Adult Rats

1 Jan 2015

Abstract excerpt

STUDY DESIGN: In vitro cell culture model. PURPOSE: We investigated the effect of diabetes mellitus (DM) on senescence of adult nucleus pulposus (NP) cells. OVERVIEW OF LITERATURE: DM is a major public health issue worldwide, especially adult-onset (type 2) DM. DM is also thought to be an important etiological factor in disc degeneration. Hyperglycemia is considered to be a major causative factor in the...

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PMID: 25901224
DOI: 10.4184/asj.2015.9.2.155

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