Article

Effect of cellular senescence on the response of human peritoneal mesothelial cells to TGF-β

2024-02-26

Abstract excerpt

<title>Abstract</title> <p>Transforming growth factor β (TGF-β) is implicated in both mesothelial-to-mesenchymal transition (MMT) and cellular senescence of human peritoneal mesothelial cells (HPMCs). We previously showed that senescent HPMCs could spontaneously acquire some phenotypic features of MMT, which in young HPMCs were induced by TGF-β. Here, we used electron microscopy, as well as global gene and protei...

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Literature Corpus work: 26aa3ff7-6b50-5499-af61-94e6e9354678
DOI: 10.21203/rs.3.rs-3931243/v1

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