Article
Changes in peritoneal mesothelial cells phenotype after chronic exposure to glucose or N-acetylglucosamine.
Translational research : the journal of laboratory and clinical medicine - 1 Dec 2007
Ciszewicz Maria, Wu George, Tam Paul, Polubinska Alicja, Breborowicz Andrzej
Abstract excerpt
Glucose is commonly used as an osmotic solute in peritoneal dialysis fluids despite vast knowledge about deleterious peritoneal and systemic effects of that solute. N-acetylglucosamine (NAG) is a solute of the comparable size to glucose, with strong anti-inflammatory properties. We compared the chronic in vitro effect of both solutes on phenotype of peritoneal mesothelial cells. Experiments were performed of...
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