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Article

Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.

Nature - 1 Mar 2007

Liu Karen J, Arron Joseph R, Stankunas Kryn, Crabtree Gerald R, Longaker Michael T

Abstract excerpt

Glycogen synthase kinase-3beta (GSK-3beta) has integral roles in a variety of biological processes, including development, diabetes, and the progression of Alzheimer's disease. As such, a thorough understanding of GSK-3beta function will have a broad impact on human biology and therapeutics. Because GSK-3beta interacts with many different pathways, its specific developmental roles remain unclear. We have...

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Identifiers

PMID: 17293880
DOI: 10.1038/nature05557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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