Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice.

The Journal of biological chemistry - 8 Jan 2016

Deák Veronika Anita, Skroblin Philipp, Dittmayer Carsten, Knobeloch Klaus-Peter, Bachmann Sebastian, Klussmann Enno

Abstract excerpt

A-kinase anchoring proteins (AKAPs) represent a family of structurally diverse proteins, all of which bind PKA. A member of this family is glycogen synthase kinase 3β (GSK3β) interaction protein (GSKIP). GSKIP interacts with PKA and also directly interacts with GSK3β. The physiological function of the GSKIP protein in vivo is unknown. We developed and characterized a conditional knock-out mouse model and found...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cleft Palate
Share to Embryo Loss

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycogen Synthase Kinase 3

Share to Glycogen Synthase Kinase 3 beta

Share to Hemizygote

Share to Palate

Share to Phosphoserine

Share to Respiration

Source

Open in PubMed Open full text

Identifiers

PMID: 26582204
DOI: 10.1074/jbc.M115.701177
PMCID: PMC4705389

Genes

GSKIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice.PMID 26582204Read ↗

Role of GSK-3β in the osteogenic differentiation of palatal mesenchyme.Semantic proximity Read ↗

Systematic analysis of palatal transcriptome to identify cleft palate genes within TGFβ3-knockout mice alleles: RNA-Seq analysis of TGFβ3 Mice.Semantic proximity Read ↗

Novel reporter alleles of GSK-3α and GSK-3β.Semantic proximity Read ↗

Gene Regulatory Networks and Signaling Pathways in Palatogenesis and Cleft Palate: A Comprehensive ReviewSemantic proximity Read ↗

Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.Semantic proximity Read ↗

Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice.Semantic proximity Read ↗

Molecular control of secondary palate development.Semantic proximity Read ↗

Glycogen synthase kinase 3 alpha/beta deletion induces precocious growth plate remodeling and cell loss in miceSemantic proximity Read ↗

AKAP3-mediated type I PKA signaling is required for mouse sperm hyperactivation and fertilitySemantic proximity Read ↗

Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development.Semantic proximity Read ↗

Biological Mechanisms in Palatogenesis and Cleft PalateSemantic proximity Read ↗

Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.