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Article

Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma.

International journal of cancer - 15 Jun 2007

Landi Stefano, Gemignani Federica, Neri Monica, Barale Roberto, Bonassi Stefano, Bottari Fabio, Canessa Pier Aldo, Canzian Federico, Ceppi Marcello, Filiberti Rosangela, Ivaldi Gian Paolo, Mencoboni Manlio, Scaruffi Paola, Tonini Gian Paolo, Mutti Luciano, Puntoni Riccardo

Abstract excerpt

Individual response to oxidative stress, due to exposure to asbestos fibres plays a significant role in the malignant pleural mesothelioma (MPM) etiology. The differential impact on MPM risk of polymorphic alleles of glutathione-S-transferases (GSTs) and manganese superoxide dismutase (MnSOD/SOD2) genes involved in the defence against oxidative damage has been investigated. Ninety cases of MPM and 395 controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17290392
DOI: 10.1002/ijc.22590

Genes

GSTA2
GSTA4
GSTM1
GSTM3
GSTP1
GSTT1
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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