Article
Metabolic genotypes as modulators of asbestos-related pleural malignant mesothelioma risk: a comparison of Finnish and Italian populations.
International journal of hygiene and environmental health - 1 Jul 2006
Neri Monica, Taioli Emanuela, Filiberti Rosangela, Paolo Ivaldi Giovanni, Aldo Canessa Pier, Verna Anna, Marroni Paola, Puntoni Riccardo, Hirvonen Ari, Garte Seymour
Abstract excerpt
The role of CYP1A1, GSTM1, GSTT1, EPHX1, and NAT2 genotypes in susceptibility to malignant mesothelioma (MM) was compared in two case-control studies, previously conducted in two countries where different types of asbestos fibers have been used [Hirvonen et al., 1995. Inherited GSTM1 and NAT2 defects as concurrent risk modifiers in asbestos-related human malignant mesothelioma. Cancer Res. 55, 2981-2983; Hirvonen...
Topics
- Arylamine N-Acetyltransferase
- Asbestos
- Case-Control Studies
- Epoxide Hydrolases
- Finland
- Genetic Predisposition to Disease
- Genotype
- Glutathione Transferase
- Humans
- Italy
- Mesothelioma
- Occupational Exposure