Article
Asbestos exposure, manganese superoxide dismutase (MnSOD) genotype, and lung cancer risk.
Journal of occupational and environmental medicine - 1 Jun 2004
Wang Lisa I, Neuberg Donna, Christiani David C
Abstract excerpt
To assess whether differences in genetic susceptibility to oxidative stress modify asbestos-related lung cancer risk (caused by lung inflammation, free radical production), we examined possible interactions between manganese superoxide dismutase (MnSOD) genotypes and asbestos in a hospital-based case-control study of 811 white lung cancer cases and 957 friend/spouse controls. Cumulative lifetime asbestos exposure...
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