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Article

The role of single nucleotide polymorphisms related to iron homeostasis in mesothelioma susceptibility after asbestos exposure: a genetic study on autoptic samples.

Frontiers in public health - 1 Jan 2023

Grignani Pierangela, Visonà Silvia Damiana, Fronda Maria Vittoria, Borrelli Paola, Monti Maria Cristina, Bertoglio Barbara, Conti Adelaide, Fattorini Paolo, Previderè Carlo

Abstract excerpt

Asbestos-related diseases still represent a major public health problem all over the world. Among them, malignant mesothelioma (MM) is a poor-prognosis cancer, arising from the serosal lining of the pleura, pericardium and peritoneum, triggered by asbestos exposure. Literature data suggest the key role of iron metabolism in the coating process leading to the formation of asbestos bodies, considered to be both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mesothelioma, Malignant

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Share to Polymorphism, Single Nucleotide

Share to Tumor Microenvironment

Source

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Identifiers

PMID: 37942251
DOI: 10.3389/fpubh.2023.1236558
PMCID: PMC10628177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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