Article
Iron signature in asbestos-induced malignant pleural mesothelioma: A population-based autopsy study.
Journal of toxicology and environmental health. Part A - 1 Jan 2016
Crovella Sergio, Bianco Anna Monica, Vuch Joseph, Zupin Luisa, Moura Ronald Rodrigues, Trevisan Elisa, Schneider Manuela, Brollo Alessandro, Nicastro Enza Maria, Cosenzi Alessandro, Zabucchi Giuliano, Borelli Violetta
Abstract excerpt
Malignant pleural mesothelioma (MPM) is an aggressive cancer with poor prognosis. The development of MPM is frequently linked to inhalation of asbestos fibers. A genetic component of susceptibility to this disease is suggested by the observation that some individuals develop MPM following lower doses of asbestos exposure, whereas others exposed to higher quantities do not seem to be affected. This hypothesis is...
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