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Article

Genetic susceptibility to malignant pleural mesothelioma and other asbestos-associated diseases.

Mutation research - 1 Jan 2000

Neri Monica, Ugolini Donatella, Dianzani Irma, Gemignani Federica, Landi Stefano, Cesario Alfredo, Magnani Corrado, Mutti Luciano, Puntoni Riccardo, Bonassi Stefano

Abstract excerpt

Exposure to asbestos fibers is a major risk factor for malignant pleural mesothelioma (MPM), lung cancer, and other non-neoplastic conditions, such as asbestosis and pleural plaques. However, in the last decade many studies have shown that polymorphism in the genes involved in xenobiotic and oxidative metabolism or in DNA repair processes may play an important role in the etiology and pathogenesis of these...

Read the complete abstract on PubMed

Topics

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18420450
DOI: 10.1016/j.mrrev.2008.02.002

Genes

GSTM1
SOD2
GSTT1
MPO
NAT2
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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