Article
A genome-wide association study for malignant mesothelioma risk.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2013
Cadby Gemma, Mukherjee Sutapa, Musk A W Bill, Reid Alison, Garlepp Mike, Dick Ian, Robinson Cleo, Hui Jennie, Fiorito Giovanni, Guarrera Simonetta, Beilby John, Melton Phillip E, Moses Eric K, Ugolini Donatella, Mirabelli Dario, Bonassi Stefano, Magnani Corrado, Dianzani Irma, Matullo Giuseppe, Robinson Bruce, Creaney Jenette, Palmer Lyle J
Abstract excerpt
Malignant mesothelioma (MM) is a uniformly fatal tumour of mesothelial cells. MM is caused by exposure to asbestos however most individuals with documented asbestos exposure do not develop MM. Although MM appears to aggregate within families, the genetics of MM susceptibility is a relatively unexplored area. The aim of the current study was to identify genetic factors that contribute to MM risk. A genome-wide...
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