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Article

Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process.

Molecular pharmacology - 1 May 2007

Lisk Godfrey, Scott Seth, Solomon Tsione, Pillai Ajay D, Desai Sanjay A

Abstract excerpt

Human red blood cells infected with the malaria parasite Plasmodium falciparum have markedly increased permeabilities to diverse organic and inorganic solutes. The plasmodial surface anion channel (PSAC), recently identified with electrophysiological methods, contributes to the uptake of many small solutes. In this study, we explored the effects of known PSAC antagonists on transport of different solutes. We were...

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PMID: 17287402
DOI: 10.1124/mol.106.030734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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