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Article

Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum.

The Journal of biological chemistry - 29 Apr 2005

Desai Sanjay A, Alkhalil Abdulnaser, Kang Myungsa, Ashfaq Umar, Nguyen My-Le

Abstract excerpt

The plasmodial surface anion channel (PSAC) is an unusual ion channel induced on the human red blood cell membrane after infection with the malaria parasite, Plasmodium falciparum. Because PSAC is permeant to small metabolic precursors essential for parasite growth and is present on red blood cells infected with geographically divergent parasite isolates, it may be an ideal target for future antimalarial...

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PMID: 15701633
DOI: 10.1074/jbc.M414629200

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