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Article

Mutations at the GABA receptor selectivity filter: a possible role for effective charges.

The Journal of physiology - 15 Apr 2003

Wotring V E, Miller T S, Weiss D S

Abstract excerpt

An important feature of ligand-gated ion channels is their exquisite ability to discriminate between ions. Still, little is known about the mechanisms underlying, or structural determinates of, this ability. We examined the structural elements underlying the ionic selectivity of rho1 GABA receptors expressed in Xenopus oocytes and human embryonic kidney cells using site-directed mutagenesis and two-electrode...

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Identifiers

PMID: 12626678
DOI: 10.1113/jphysiol.2002.032045
PMCID: PMC2342860

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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