Article
The substrate anion selectivity filter in the human erythrocyte Cl-/HCO3- exchange protein, AE1.
The Journal of biological chemistry - 28 May 2004
Zhu Quansheng, Casey Joseph R
Abstract excerpt
AE1 facilitates Cl-/HCO3- exchange across the erythrocyte membrane. To identify residues involved in substrate selection and translocation, we prepared an array of single cysteine mutants in an otherwise cysteineless background. These mutants spanning the C-terminal portion of the AE1 membrane do...
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