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Article

Effects of single SNPs, haplotypes, and whole-genome LD maps on accuracy of association mapping.

Genetic epidemiology - 1 Apr 2007

Maniatis Nikolas, Collins Andrew, Morton Newton E

Abstract excerpt

We describe an association mapping approach that utilizes linkage disequilibrium (LD) maps in LD units (LDU). This method uses composite likelihood to combine information from all single marker tests, and applies a model with a parameter for the location of the causal polymorphism. Previous analyses of the poor drug metabolizer phenotype provided evidence of the substantial utility of LDU maps for disease gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17285621
DOI: 10.1002/gepi.20199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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