Article
The impact of SNP density on fine-scale patterns of linkage disequilibrium.
Human molecular genetics - 15 Mar 2004
Ke Xiayi, Hunt Sarah, Tapper William, Lawrence Robert, Stavrides George, Ghori Jilur, Whittaker Pamela, Collins Andrew, Morris Andrew P, Bentley David, Cardon Lon R, Deloukas Panos
Abstract excerpt
Linkage disequilibrium (LD) is a measure of the degree of association between alleles in a population. The detection of disease-causing variants by association with neighbouring single nucleotide polymorphisms (SNPs) depends on the existence of strong LD between them. Previous studies have indica...
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