Article
Symbolic modeling of epistasis.
Human heredity - 1 Jan 2007
Moore Jason H, Barney Nate, Tsai Chia-Ti, Chiang Fu-Tien, Gui Jiang, White Bill C
Abstract excerpt
The workhorse of modern genetic analysis is the parametric linear model. The advantages of the linear modeling framework are many and include a mathematical understanding of the model fitting process and ease of interpretation. However, an important limitation is that linear models make assumptions about the nature of the data being modeled. This assumption may not be realistic for complex biological systems such...
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