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Article

A Belief Degree-Associated Fuzzy Multifactor Dimensionality Reduction Framework for Epistasis Detection.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Rahaman Saifur, Wong Ka-Chun

Abstract excerpt

Epistasis is a challenge in prediction, classification, and suspicion of human genetic diseases. Many technologies, methods, and tools have been developed for epistasis detection. Multifactor dimensionality reduction (MDR) is the method commonly used in epistasis detection. It uses two class groups-high risk and low risk-in human genetic disease and complex genetic traits. However, it cannot handle uncertainties...

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PMID: 33733364
DOI: 10.1007/978-1-0716-0947-7_19

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