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Connecting the dots between genes, biochemistry, and disease susceptibility: systems biology modeling in human genetics.

Molecular genetics and metabolism - 1 Feb 2005

Moore Jason H, Boczko Erik M, Summar Marshall L

Abstract excerpt

Understanding how DNA sequence variations impact human health through a hierarchy of biochemical and physiological systems is expected to improve the diagnosis, prevention, and treatment of common, complex human diseases. We have previously developed a hierarchical dynamic systems approach based on Petri nets for generating biochemical network models that are consistent with genetic models of disease...

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PMID: 15670716
DOI: 10.1016/j.ymgme.2004.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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