Article
A complete classification of epistatic two-locus models.
BMC genetics - 19 Feb 2008
Hallgrímsdóttir Ingileif B, Yuster Debbie S
Abstract excerpt
BACKGROUND: The study of epistasis is of great importance in statistical genetics in fields such as linkage and association analysis and QTL mapping. In an effort to classify the types of epistasis in the case of two biallelic loci Li and Reich listed and described all models in the simplest case of 0/1 penetrance values. However, they left open the problem of finding a classification of two-locus models with...
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