Article
An entropy test for single-locus genetic association analysis.
BMC genetics - 23 Mar 2010
Ruiz-Marín Manuel, Matilla-García Mariano, Cordoba José Antonio García, Susillo-González Juan Luis, Romo-Astorga Alejandro, González-Pérez Antonio, Ruiz Agustín, Gayán Javier
Abstract excerpt
BACKGROUND: The etiology of complex diseases is due to the combination of genetic and environmental factors, usually many of them, and each with a small effect. The identification of these small-effect contributing factors is still a demanding task. Clearly, there is a need for more powerful tests of genetic association, and especially for the identification of rare effects RESULTS: We introduce a new genetic...
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