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Article

Detecting epistatic interactions contributing to quantitative traits.

Genetic epidemiology - 1 Sept 2004

Culverhouse Robert, Klein Tsvika, Shannon William

Abstract excerpt

The restricted partition method (RPM) is a partitioning algorithm for examining multi-locus genotypes as (potentially non-additive) predictors of a quantitative trait. The motivating application was to develop a robust method to examine quantitative phenotypes for epistasis (gene-gene interactions), but the method can be applied without modification to gene-environment interactions. Simulation results indicate...

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Identifiers

PMID: 15305330
DOI: 10.1002/gepi.20006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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