Article
Brain serotonin transporter binding in depressed patients with bipolar disorder using positron emission tomography.
Archives of general psychiatry - 1 Feb 2007
Oquendo Maria A, Hastings Ramin S, Huang Yung-Yu, Simpson Norman, Ogden R Todd, Hu Xian-Zhang, Goldman David, Arango Victoria, Van Heertum Ronald L, Mann J John, Parsey Ramin V
Abstract excerpt
CONTEXT: Depression in bipolar disorder is clinically indistinguishable from that observed in major depressive disorder. As in major depression, selective serotonin reuptake inhibitors targeting brain serotonin transporters are first-line treatments for bipolar depression. Associations of serotonin transporter promoter polymorphisms and bipolarity have been reported; however, research on alterations in...
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